Depression是一个主要的心理健康问18luck新利app官网题,影响大约1480万成年人在美国。为了为这种疾病开发更好的治疗方案,科学家和临床医生多年来一直致力于确定抑郁症的病因。

During this work,有一种理论抑郁症与大脑中神经递质化学物质水平的变化有关。这种变化被称为化学失衡,但what is a chemical imbalance确切地简单地说,一个chemical imbalance当大脑中的神经递质过多或过少时发生。

化学失衡的症状

神经递质是从神经细胞末梢释放出来的化学物质,它们通过传播到周围的神经细胞来传递信号。信号会传播到大脑的不同区域,从而产生情绪或引起身体反应。

神经递质有许多不同的功能,可以作用于身体的许多部位。C化学失衡症状包括:

  • 感到悲伤或绝望
  • 精力不足
  • 无法集中注意力的
  • Being agitated or irritable
  • 食欲的变化
  • 睡眠模式的变化
  • Having feelings of imminent danger
  • 感到麻木或缺乏同情心
  • 严重的情绪波动
  • 自杀或伤害他人的想法
  • 无法执行日常任务
  • Getting emotional or crying uncontrollably for no reason
  • 退出常规活动和社交活动
  • Drastic changes in behavior
  • 对你通常喜欢做的事情缺乏兴趣
  • 感到焦虑或紧张

抑郁或焦虑情绪会导致自杀想法。如果你或你所爱的人有自杀倾向,打电话给全国自杀预防热线1-800-273-8255

这个Role of Brain Chemistry in Depression

有一定的原因parts of the brain that control mood还有情绪。大脑的这些部分,包括海马、丘脑和杏仁核,被认为是对抑郁症患者有影响.这些部分负责长期记忆、感官信息和情绪,如愤怒、快乐、悲伤和恐惧。

神经递质水平的变化是什么导致大脑中的化学物质失衡。改变可以影响神经递质水平the intensity of signals between nerves. A weakened signal can occur when a nerve ending doesn’t make or release enough of a neurotransmitter. Once the neurotransmitter is released, it can be reabsorbed too quickly by the nerve endings, which would also weaken the signal. The responding cell could also have altered receptor levels, causing increased or decreased reception.

Scientists believed化学失衡与抑郁由于不平衡是如何影响大脑控制情绪的区域的,这两者之间存在联系。化学失衡理论认为抑郁症与低水平的神经递质血清素和去甲肾上腺素有关。

这个Reality Behind the Chemical Imbalance Myth

当针对神经递质的药物能够缓解抑郁症状时,化学失衡理论发展起来。例如,单胺氧化酶抑制剂(MAOIs)会增加神经递质的数量,并可以治疗抑郁症in some patients.

However, recent scientific evidence hasfailed to prove this theory唯一的证据是抑郁症患者血液中的神经递质较少,一些患者的抑郁症症状通过增加神经递质的药物得到缓解。

这个se findings are not always consistent and may not explain the underlying biology of depression. First of all, medications that increase neurotransmitters are not effective for all patients. This suggests that there are other factors contributing to depression. Additionally, levels of neurotransmitters in the blood may not represent levels of neurotransmitters in the brain, which is extremely hard to measure. Neurotransmitter levels fluctuate greatly in the blood, which could be the result of neurotransmitters being produced by other parts of the body.

这个chemical imbalance myth被认为是由制药公司维持。这个companies advertise the chemical imbalance theory as fact to encourage consumers to buy their drugs. The myth has also been adopted by society as a way to take the blame of depression away from the person experiencing it. It states they have depression because there is a fundamental flaw in their biology. This helps to remove the stigma associated with the disorder, but it does not accurately represent the underlying biology.

实际上,什么导致抑郁症这比化学物质的不平衡要复杂得多。有很多environmental and genetic factors这也可以发挥作用。

抑郁症药物和治疗

抑郁症治疗通常使用药物和治疗。

许多的depression medications增加大脑中5-羟色胺和其他神经递质的水平。它们通过阻止神经末梢重新吸收神经递质或阻止神经递质分解来实现这一点。在这两种情况下,神经递质更容易向周围神经发出信号。治疗抑郁症的一些常用药物包括:

  • SSRIsselective serotonin reuptake inhibitors,阻止血清素的再吸收
  • 去甲肾上腺素再摄取抑制剂或血清素去甲肾上腺素再摄取抑制剂,阻止血清素的再吸收and norepinephrine
  • TCAs或三环antidepressants,阻止血清素和去甲肾上腺素的再吸收
  • NDRIs或去甲肾上腺素多巴胺再摄取抑制剂,which prevent reabsorption of norepinephrine and dopamine
  • MAOIs或单胺氧化酶抑制剂,防止去甲肾上腺素、血清素和多巴胺的分解

通常,药物治疗不足以缓解抑郁症状。除了药物治疗外,治疗也非常有益。抑郁症治疗的一个例子是认知行为疗法。这个goal of this therapy is to modify the thought processes that might be contributing to depression.

还有一些方法化学不平衡处理没有药物治疗,如运动、饮食和暴露在阳光下。

如果不进行治疗,一些人可能会使用药物来应对抑郁症。如果你或你所爱的人正在与抑郁症与物质成瘾,康复村可以提供帮助。要了解更多关于治疗计划的信息,今天打电话to speak with a representative.

Medical Disclaimer:恢复村aims to improve the quality of life for people struggling with a substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare provider.

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